HFrEF patients were recruited between October 2012 and December 2015 patients with HFpEF were enrolled between September 2013 and December 2017.ĭata collection included patient demographics, clinical symptoms, co-morbidities, and medications. Recruitment of patients in ASIAN-HF was in two phases, through investigation sites which covered a broad spectrum of medical, cardiology, and HF specialty units, admitting patients with acute HF and conducting outpatient follow-up of patients with chronic HF. In addition, 99.5% of HFpEF patients had echocardiographic evidence for diastolic dysfunction. They were categorized as HFrEF and HFpEF based on left ventricular ejection fraction <40% and ≥50%, respectively. All patients enrolled in ASIAN-HF had a validated clinical diagnosis of HF by independent site investigators (based on symptoms, signs, and clinical decompensation within 6 months).
![stata mp 13 2 core product stata mp 13 2 core product](https://venturebeat.com/wp-content/uploads/2018/04/starwars-ar2.jpg)
8 The study complied with the Declaration of Helsinki, and ethics approvals were obtained at all sites. Exclusion criteria have previously been described. Patients were >18 years and provided written informed consent. Consecutive patients were screened in 46 medical centres across 11 Asian regions (China, Hong Kong, India, Indonesia, Japan, Korea, Malaysia, Philippines, Singapore, Taiwan, and Thailand) managing both acute and chronic HF. 8 In brief, ASIAN-HF is a prospective, observational, multinational registry of Asian patients with symptomatic HF.
![stata mp 13 2 core product stata mp 13 2 core product](https://www.stata.com/stata15/img/new-in-stata15.png)
Participants were identified from the Asian Sudden Cardiac Death in HF (ASIAN-HF) registry ( Identifier: NCT01633398). We aimed to characterize ethnic differences in prevalence, clinical correlates, and outcomes of AF in HF with preserved and reduced ejection fraction (HFpEF and HFrEF) across Asia.
![stata mp 13 2 core product stata mp 13 2 core product](https://m.media-amazon.com/images/I/71az8oR+jwL._AC_SS450_.jpg)
8 It is unknown if ethnic differences in AF prevalence and clinical correlates within Asia are present. 5 The ethnic differences in AF prevalence in HF, while striking, remain poorly understood.Īsia is geographically vast, with significant heterogeneity among patients with HF not only by region but also by ethnicity. 3- 7 A large US registry reported a higher prevalence of AF among white HF patients compared with blacks, Hispanics, and Asians 3 while a prospective Asia Pacific study showed a distinctly lower prevalence of AF among Singaporean–Asian compared with New Zealand European HF patients. 1, 2 Beyond traditional risk factors, there is growing evidence of ethnic influences on the prevalence of AF in the context of HF. ConclusionsĪmong patients with HF across Asia, clinical correlates and adverse outcomes associated with AF are similar across ethnicities however, there are striking ethnic variations in the prevalence of AF that are not accounted for by known risk factors.Ītrial fibrillation (AF) is the most common arrhythmia in heart failure (HF) and is associated with an increased risk of stroke, HF hospitalisation and mortality. AF was associated with poorer quality of life and increased risk of 1 year all-cause mortality or HF hospitalisation (adjusted hazard ratio 1.39, 95% CI 1.18–1.63) regardless of ethnicity.
![stata mp 13 2 core product stata mp 13 2 core product](https://venturebeat.com/wp-content/uploads/2018/04/img_731d0894c81f-1.jpeg)
Interaction between ethnicity and region was observed among Indians, with Southeast Asian Indians having higher odds of AF (AOR 3.01, 95% CI 1.60–5.67) compared with South Asian Indians. Compared with Chinese ethnicity, Japanese/Koreans had higher odds of AF in HFrEF (AOR 1.76, 95% CI 1.40–2.21), while Indians had lower odds in HFrEF (AOR 0.18, 95% CI 0.13–0.24) and HFpEF (AOR 0.28, 95% CI 0.16–0.49) even after adjusting for clinical covariates. Diabetes was associated with lower odds of AF in HFrEF and HFpEF (AOR 0.58, 95% CI 0.39–0.84) regardless of ethnicity. Clinical correlates of AF were similar across ethnicities and included older age, prior stroke, higher NT-proBNP, and larger left atria. Methods and resultsĪmong 5504 patients with HF prospectively recruited across 11 Asian regions using identical protocols in the Asian Sudden Cardiac Death in Heart Failure study (mean age 61 ± 13 years, 27% women, 83% HFrEF), 1383 (25%) had AF defined as a history of AF and/or AF/flutter on baseline electrocardiogram. NET (22) simulation (22) Visualization (21) Measuring instrument (20) TO DEAL (19) UI (19) Raspberry Pi (17) Deep learning (17) Machine learning (machine learning) (17) DNA (16) Video / Video (16) modeling (16) Metashape (16) Arduino (15) JavaScript (15) ROS (15) 3D model (15) Image processing (15) protocol (15) Psychology (15) Education (15) SLAM (14) (I.e.We aimed to characterize ethnic differences in prevalence, clinical correlates, and outcomes of atrial fibrillation (AF) in heart failure (HF) with preserved and reduced ejection fraction (HFpEF and HFrEF) across Asia. Analysis tool (42) VR (39) SBC (35) Small SBC (35) Statistical analysis (33) Spectrum (33) instrumentation (31) 3D camera (28) RealSense (27) IoT (26) In-vehicle (25) Robot arm (24) AR (23) Depth camera (23).